Lineage for d1yhva_ (1yhv A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2220339Protein pak1 [56146] (1 species)
    OPK group; PAK/STE20 subfamily; serine/threonine kinase
  7. 2220340Species Human (Homo sapiens) [TaxId:9606] [56147] (19 PDB entries)
  8. 2220346Domain d1yhva_: 1yhv A: [162206]
    automated match to d1f3mc_
    mutant

Details for d1yhva_

PDB Entry: 1yhv (more details), 1.8 Å

PDB Description: Crystal Structure of PAK1 kinase domain with two point mutations (K299R, T423E)
PDB Compounds: (A:) Serine/threonine-protein kinase PAK 1

SCOPe Domain Sequences for d1yhva_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1yhva_ d.144.1.7 (A:) pak1 {Human (Homo sapiens) [TaxId: 9606]}
sdeeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnlqqqpk
keliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaa
vcreclqaleflhsnqvihrdiksdnillgmdgsvkltdfgfcaqitpeqskrsemvgtp
ywmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpe
klsaifrdflnrcldmdvekrgsakellqhqflkiakplssltpliaaakeat

SCOPe Domain Coordinates for d1yhva_:

Click to download the PDB-style file with coordinates for d1yhva_.
(The format of our PDB-style files is described here.)

Timeline for d1yhva_: