SCOPe 2.06: Domain d1xkdb_: 1xkd B:

Lineage for d1xkdb_ (1xkd B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
   the constituent families form similar dimers

5. Family c.77.1.0: automated matches [191423] (1 protein)
   not a true family

6. Protein automated matches [190603] (16 species)
   not a true protein

7. Species Aeropyrum pernix [TaxId:272557] [188121] (1 PDB entry)

8. Domain d1xkdb_: 1xkd B: [162082]
   automated match to d1hqsa_
   complexed with ca, ict, nap

Details for d1xkdb_

PDB Entry: 1xkd, 2.3 Å

PDB Description: ternary complex of isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix

PDB Compounds: (B:) isocitrate dehydrogenase

SCOPe Domain Sequences for d1xkdb_:

Sequence, based on SEQRES records:

>d1xkdb_ c.77.1.0 (B:) automated matches {Aeropyrum pernix [TaxId: 272557]}
sppctteelspppggslveysggslrvpdnpvvafirgdgvgpevvesalkvvdaavkkv
yggsrrivwwellaghlarekcgellpkatlegirlarvalkgpletpvgtgyrslnvai
rqaldlyanirpvryygqpaphkyadrvdmvifrentedvyagiewphdspeaarirrfl
aeefgisiredagigvkpisrfatrrlmeralewalrngntvvtimhkgnimkytegafm
rwayevalekfrehvvteqevqekyggvrpegkilvndriadnmlqqiitrpwdyqviva
pnlngdyisdaasalvggigmaagmnmgdgiavaepvhgtapkyagkdlinpsaeilsas
lligefmgwrevksiveyairkavqskkvtqdlarhmpgvqplrtseytetliayidead
l

Sequence, based on observed residues (ATOM records):

>d1xkdb_ c.77.1.0 (B:) automated matches {Aeropyrum pernix [TaxId: 272557]}
sppctteelspppggslveysggslrvpdnpvvafirgdgvgpevvesalkvvdaavkkv
gsrrivwwellaghlarekcgellpkatlegirlarvalkgpletpvgtgyrslnvairq
aldlyanirpvryygqpaphkyadrvdmvifrentedvyagiewphdspeaarirrflae
efgisiredagigvkpisrfatrrlmeralewalrngntvvtimhkgnimkytegafmrw
ayevalekfrehvvteqevqekyggvrpegkilvndriadnmlqqiitrpwdyqvivapn
lngdyisdaasalvggigmaagmnmgdgiavaepvhgtapkyagkdlinpsaeilsasll
igefmgwrevksiveyairkavqskkvtqdlarhmpgvqplrtseytetliayideadl

Timeline for d1xkdb_:

• d1xkdb_ first appeared in SCOPe 2.01
  
• d1xkdb_ appears in SCOPe 2.05
  
• d1xkdb_ appears in SCOPe 2.07
  
• d1xkdb_ appears in the current release, SCOPe 2.08