SCOPe 2.04: Domain d1xg4b_: 1xg4 B:

Lineage for d1xg4b_ (1xg4 B:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (8 families)

5. Family c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like [88704] (4 proteins)
   forms a swapped dimer

6. Protein 2-methylisocitrate lyase [89499] (2 species)

7. Species Escherichia coli [TaxId:562] [89500] (4 PDB entries)

8. Domain d1xg4b_: 1xg4 B: [162069]
   automated match to d1oqfa_
   complexed with ict, mg; mutant

Details for d1xg4b_

PDB Entry: 1xg4, 1.6 Å

PDB Description: crystal structure of the c123s 2-methylisocitrate lyase mutant from escherichia coli in complex with the inhibitor isocitrate

PDB Compounds: (B:) Probable methylisocitrate lyase

SCOPe Domain Sequences for d1xg4b_:

Sequence; same for both SEQRES and ATOM records:

>d1xg4b_ c.1.12.7 (B:) 2-methylisocitrate lyase {Escherichia coli [TaxId: 562]}
lhspgkafraaltkenplqivgtinanhallaqragyqaiylsgggvaagslglpdlgis
tlddvltdirritdvcslpllvdadigfgssafnvartvksmikagaaglhiedqvgakr
sghrpnkaivskeemvdriraavdaktdpdfvimartdalavegldaaieraqayveaga
emlfpeaitelamyrqfadavqvpilanitefgatplfttdelrsahvamalyplsafra
mnraaehvynvlrqegtqksvidtmqtrnelyesinyyqyeekldn

Timeline for d1xg4b_:

• d1xg4b_ first appeared in SCOPe 2.01
  
• d1xg4b_ appears in SCOPe 2.03
  
• d1xg4b_ appears in SCOPe 2.05
  
• d1xg4b_ appears in the current release, SCOPe 2.08