SCOPe 2.02: Domain d1x7tb_: 1x7t B:

Lineage for d1x7tb_ (1x7t B:)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.3: Prealbumin-like [49451] (7 superfamilies)
   sandwich; 7 strands in 2 sheets, greek-key
   variations: some members have additional 1-2 strands to common fold

4. Superfamily b.3.4: Transthyretin (synonym: prealbumin) [49472] (2 families)

5. Family b.3.4.1: Transthyretin (synonym: prealbumin) [49473] (2 proteins)

6. Protein Transthyretin (synonym: prealbumin) [49474] (5 species)
   sandwich; 8 strands in 2 sheets

7. Species Human (Homo sapiens) [TaxId:9606] [49475] (150 PDB entries)
   Uniprot P02766 31-143

8. Domain d1x7tb_: 1x7t B: [162043]
   automated match to d1eta1_

Details for d1x7tb_

PDB Entry: 1x7t, 1.6 Å

PDB Description: structure of ttr r104h: a non-amyloidogenic variant with protective clinical effects

PDB Compounds: (B:) Transthyretin

SCOPe Domain Sequences for d1x7tb_:

Sequence, based on SEQRES records:

>d1x7tb_ b.3.4.1 (B:) Transthyretin (synonym: prealbumin) {Human (Homo sapiens) [TaxId: 9606]}
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprhytiaallspysysttavvt

Sequence, based on observed residues (ATOM records):

>d1x7tb_ b.3.4.1 (B:) Transthyretin (synonym: prealbumin) {Human (Homo sapiens) [TaxId: 9606]}
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsprhytiaallspysysttavvt

Timeline for d1x7tb_:

• d1x7tb_ first appeared in SCOPe 2.01
  
• d1x7tb_ appears in SCOPe 2.03
  
• d1x7tb_ appears in the current release, SCOPe 2.08