SCOPe 2.08: Domain d1x7eb_: 1x7e B:

Lineage for d1x7eb_ (1x7e B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d1x7eb_: 1x7e B: [162038]
   automated match to d1g50a_
   complexed with 244

Details for d1x7eb_

PDB Entry: 1x7e, 2.8 Å

PDB Description: crystal structure of estrogen receptor alpha complexed with way-244

PDB Compounds: (B:) Estrogen receptor 1 (alpha)

SCOPe Domain Sequences for d1x7eb_:

Sequence, based on SEQRES records:

>d1x7eb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpvkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml
dahrl

Sequence, based on observed residues (ATOM records):

>d1x7eb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpvkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytfleekdhihrvldkitdtlihlma
kagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemldahrl

Timeline for d1x7eb_:

• d1x7eb_ first appeared in SCOPe 2.01
  
• d1x7eb_ appears in SCOPe 2.07