SCOPe 2.08: Domain d1x0lb_: 1x0l B:

Lineage for d1x0lb_ (1x0l B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
   the constituent families form similar dimers

5. Family c.77.1.0: automated matches [191423] (1 protein)
   not a true family

6. Protein automated matches [190603] (25 species)
   not a true protein

7. Species Thermus thermophilus [TaxId:274] [188105] (1 PDB entry)

8. Domain d1x0lb_: 1x0l B: [162019]
   automated match to d1wpwa_

Details for d1x0lb_

PDB Entry: 1x0l, 1.85 Å

PDB Description: Crystal structure of tetrameric homoisocitrate dehydrogenase from an extreme thermophile, Thermus thermophilus

PDB Compounds: (B:) Homoisocitrate dehydrogenase

SCOPe Domain Sequences for d1x0lb_:

Sequence, based on SEQRES records:

>d1x0lb_ c.77.1.0 (B:) automated matches {Thermus thermophilus [TaxId: 274]}
ayricliegdgighevipaarrvleatglplefveaeagwetferrgtsvpeetvekils
chatlfgaatsptrkvpgffgairylrrrldlyanvrpaksrpvpgsrpgvdlvivrent
eglyveqerryldvaiadaviskkaserigraalriaegrprktlhiahkanvlpltqgl
fldtvkevakdfplvnvqdiivdncamqlvmrperfdvivttnllgdilsdlaaglvggl
glapsgnigdttavfepvhgsapdiagkgianptaailsaammldylgekeaakrvekav
dlvlergprtpdlggdatteafteavvealksl

Sequence, based on observed residues (ATOM records):

>d1x0lb_ c.77.1.0 (B:) automated matches {Thermus thermophilus [TaxId: 274]}
ayricliegdgighevipaarrvleatglplefveaeagwetferrgtsvpeetvekils
chatlfgaatvpgffgairylrrrldlyanvrpaksrpvpgsrpgvdlvivrenteglyv
eqerryldvaiadaviskkaserigraalriaegrprktlhiahkanvlpltqglfldtv
kevakdfplvnvqdiivdncamqlvmrperfdvivttnllgdilsdlaaglvgglglaps
gnigdttavfepvhgsaiagkgianptaailsaammldylgekeaakrvekavdlvlerg
prtpdlggdatteafteavvealksl

Timeline for d1x0lb_:

• d1x0lb_ first appeared in SCOPe 2.01
  
• d1x0lb_ appears in SCOPe 2.07