SCOPe 2.01: Domain d1w5pa_: 1w5p A:

Lineage for d1w5pa_ (1w5p A:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (2 proteins)
   hybrid of classes I and II aldolase

6. Protein automated matches [190088] (3 species)
   not a true protein

7. Species Pseudomonas aeruginosa [TaxId:208964] [188066] (6 PDB entries)

8. Domain d1w5pa_: 1w5p A: [161901]
   automated match to d1gzgb_
   complexed with edo, fmt, gol, k, mg, so4, zn; mutant

Details for d1w5pa_

PDB Entry: 1w5p, 1.55 Å

PDB Description: stepwise introduction of zinc binding site into porphobilinogen synthase of pseudomonas aeruginosa (mutations a129c, d131c, d139c, p132e)

PDB Compounds: (A:) delta-aminolevulinic acid dehydratase

SCOPe Domain Sequences for d1w5pa_:

Sequence, based on SEQRES records:

>d1w5pa_ c.1.10.3 (A:) automated matches {Pseudomonas aeruginosa [TaxId: 208964]}
anraypytrlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgverlsi
dqllieaeewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfpelgii
tdvclceftthgqcgildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdgrigai
realesaghtnvrvmaysakyasayygpfrdavgsasnlgkgnkatyqmdpansdealhe
vaadlaegadmvmvkpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngwlaesv
ilesltafkragadgiltyfakqaaeqlrrg

Sequence, based on observed residues (ATOM records):

>d1w5pa_ c.1.10.3 (A:) automated matches {Pseudomonas aeruginosa [TaxId: 208964]}
anraypytrlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgverlsi
dqllieaeewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfpelgii
tdvclceftthgqcgildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdgrigai
realesaghtnvrvmaysakyasayygpfrdavnkatyqmdpansdealhevaadlaega
dmvmvkpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngwlaesvilesltafk
ragadgiltyfakqaaeqlrrg

Timeline for d1w5pa_:

• d1w5pa_ is new in SCOPe 2.01-stable
  
• d1w5pa_ appears in SCOPe 2.02
  
• d1w5pa_ appears in the current release, SCOPe 2.08