SCOPe 2.08: Domain d1w54a_: 1w54 A:

Lineage for d1w54a_ (1w54 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (2 proteins)
   hybrid of classes I and II aldolase
   automatically mapped to Pfam PF00490

6. Protein automated matches [190088] (4 species)
   not a true protein

7. Species Pseudomonas aeruginosa [TaxId:287] [187506] (8 PDB entries)

8. Domain d1w54a_: 1w54 A: [161891]
   automated match to d1gzgb_
   complexed with fmt, k, mg, zn; mutant

Details for d1w54a_

PDB Entry: 1w54, 2.2 Å

PDB Description: stepwise introduction of a zinc binding site into porphobilinogen synthase from pseudomonas aeruginosa (mutation d139c)

PDB Compounds: (A:) delta-aminolevulinic acid dehydratase

SCOPe Domain Sequences for d1w54a_:

Sequence, based on SEQRES records:

>d1w54a_ c.1.10.3 (A:) automated matches {Pseudomonas aeruginosa [TaxId: 287]}
trlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgverlsidqlliea
eewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfpelgiitdvaldp
ftthgqcgildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdgrigairealesa
ghtnvrvmaysakyasayygpfrdavgsasnlgkgnkatyqmdpansdealhevaadlae
gadmvmvkpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngwlaesvileslta
fkragadgiltyfakqaaeqlrrg

Sequence, based on observed residues (ATOM records):

>d1w54a_ c.1.10.3 (A:) automated matches {Pseudomonas aeruginosa [TaxId: 287]}
trlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgverlsidqlliea
eewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfpelgiitdvaldp
ftthgqcgildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdgrigairealesa
ghtnvrvmaysakyasayygpfrdaatyqmdpansdealhevaadlaegadmvmvkpgmp
yldivrrvkdefraptfvyqvsgeyamhmgaiqngwlaesvilesltafkragadgilty
fakqaaeqlrrg

Timeline for d1w54a_:

• d1w54a_ first appeared in SCOPe 2.01
  
• d1w54a_ appears in SCOPe 2.07