SCOPe 2.03: Domain d1tzsa_: 1tzs A:

Lineage for d1tzsa_ (1tzs A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.2: Pepsin-like [50646] (11 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein automated matches [190156] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187237] (36 PDB entries)

8. Domain d1tzsa_: 1tzs A: [161791]
   automated match to d1f34a_

Details for d1tzsa_

PDB Entry: 1tzs, 2.35 Å

PDB Description: Crystal Structure of an activation intermediate of Cathepsin E

PDB Compounds: (A:) Cathepsin E

SCOPe Domain Sequences for d1tzsa_:

Sequence, based on SEQRES records:

>d1tzsa_ b.50.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
keplinyldmeyfgtisigsppqnftvifdtgssnlwvpsvyctspackthsrfqpsqss
tysqpgqsfsiqygtgslsgiigadqvsvegltvvgqqfgesvtepgqtfvdaefdgilg
lgypslavggvtpvfdnmmaqnlvdlpmfsvymssnpeggagselifggydhshfsgsln
wvpvtkqaywqialdniqvggtvmfcsegcqaivdtgtslitgpsdkikqlqnaigaapv
dgeyavecanlnvmpdvtftingvpytlsptaytlldfvdgmqfcssgfqgldihppagp
lwilgdvfirqfysvfdrgnnrvglapav

Sequence, based on observed residues (ATOM records):

>d1tzsa_ b.50.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
keplinyldmeyfgtisigsppqnftvifdtgssnlwvpsvyctspackthsrfqpsqss
tysqpgqsfsiqygtgslsgiigadqvsvegltvvgqqfgesvtepgqtfvdaefdgilg
lgypslavggvtpvfdnmmaqnlvdlpmfsvymssnpgagselifggydhshfsgslnwv
pvtkqaywqialdniqvggtvmfcsegcqaivdtgtslitgpsdkikqlqnaigaapvdg
eyavecanlnvmpdvtftingvpytlsptaytlldqfcssgfqgldihppagplwilgdv
firqfysvfdrgnnrvglapav

Timeline for d1tzsa_:

• d1tzsa_ first appeared in SCOPe 2.01
  
• d1tzsa_ appears in SCOPe 2.02
  
• d1tzsa_ appears in SCOPe 2.04
  
• d1tzsa_ appears in the current release, SCOPe 2.08