Lineage for d3ddqa1 (3ddq A:1-298)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2542927Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 2542928Species Human (Homo sapiens) [TaxId:9606] [88856] (379 PDB entries)
    Uniprot P24941
  8. 2542997Domain d3ddqa1: 3ddq A:1-298 [161653]
    Other proteins in same PDB: d3ddqa2, d3ddqb1, d3ddqb2, d3ddqc2, d3ddqd1, d3ddqd2, d3ddqd3
    automated match to d1aq1a_
    complexed with rrc, sgm

Details for d3ddqa1

PDB Entry: 3ddq (more details), 1.8 Å

PDB Description: Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor roscovitine
PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d3ddqa1:

Sequence, based on SEQRES records: (download)

>d3ddqa1 d.144.1.7 (A:1-298) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Sequence, based on observed residues (ATOM records): (download)

>d3ddqa1 d.144.1.7 (A:1-298) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtegvpstaireisllkelnhpn
ivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshr
vlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyyst
avdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpk
warqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

SCOPe Domain Coordinates for d3ddqa1:

Click to download the PDB-style file with coordinates for d3ddqa1.
(The format of our PDB-style files is described here.)

Timeline for d3ddqa1: