Lineage for d2uzlc_ (2uzl C:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 protein domains)
    members organized in the groups and subfamiles specified by the comments
  6. 2542927Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 2542928Species Human (Homo sapiens) [TaxId:9606] [88856] (376 PDB entries)
    Uniprot P24941
  8. 2543252Domain d2uzlc_: 2uzl C: [161559]
    Other proteins in same PDB: d2uzlb1, d2uzlb2, d2uzld1, d2uzld2
    automated match to d1aq1a_
    complexed with c94

Details for d2uzlc_

PDB Entry: 2uzl (more details), 2.4 Å

PDB Description: crystal structure of human cdk2 complexed with a thiazolidinone inhibitor
PDB Compounds: (C:) Cell division protein kinase 2

SCOPe Domain Sequences for d2uzlc_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2uzlc_ d.144.1.7 (C:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlr

SCOPe Domain Coordinates for d2uzlc_:

Click to download the PDB-style file with coordinates for d2uzlc_.
(The format of our PDB-style files is described here.)

Timeline for d2uzlc_: