SCOPe 2.07: Protein: Urokinase plasminogen activator surface receptor uPAR

Lineage for Protein: Urokinase plasminogen activator surface receptor uPAR

Root: SCOPe 2.07
Class g: Small proteins [56992] (98 folds)
Fold g.7: Snake toxin-like [57301] (1 superfamily)
disulfide-rich fold: nearly all-beta
Superfamily g.7.1: Snake toxin-like [57302] (4 families)
Family g.7.1.3: Extracellular domain of cell surface receptors [57354] (6 proteins)

Protein Urokinase plasminogen activator surface receptor uPAR [161128] (1 species)
duplication: tandem repeat of three similar domains; the N-terminal and C-terminal domains belong to Pfam PF00021; uPAR/Ly6

Species:

Human (Homo sapiens) [TaxId:9606] [161129] (6 PDB entries)
Uniprot Q03405 109-209! Uniprot Q03405 210-299! Uniprot Q03405 23-108

Domains for 1ywh:
1. Domain d1ywha1: 1ywh A:89-188 [145925]
  complexed with nag, ndg, so4
2. Domain d1ywha2: 1ywh A:1-82 [145926]
  complexed with nag, ndg, so4
3. Domain d1ywha3: 1ywh A:189-279 [145927]
  complexed with nag, ndg, so4
4. Domain d1ywhc1: 1ywh C:91-188 [145928]
  automated match to d1ywha1
  complexed with nag, ndg, so4
5. Domain d1ywhc2: 1ywh C:1-80 [145929]
  automated match to d1ywha2
  complexed with nag, ndg, so4
6. Domain d1ywhc3: 1ywh C:189-275 [145930]
  automated match to d1ywha3
  complexed with nag, ndg, so4
7. Domain d1ywhe1: 1ywh E:89-188 [145931]
  automated match to d1ywha1
  complexed with nag, ndg, so4
8. Domain d1ywhe2: 1ywh E:1-79 [145932]
  automated match to d1ywha2
  complexed with nag, ndg, so4
9. Domain d1ywhe3: 1ywh E:189-278 [145933]
  automated match to d1ywha3
  complexed with nag, ndg, so4
10. Domain d1ywhg1: 1ywh G:92-188 [145934]
  automated match to d1ywha1
  complexed with nag, ndg, so4
11. Domain d1ywhg2: 1ywh G:1-79 [145935]
  automated match to d1ywha2
  complexed with nag, ndg, so4
12. Domain d1ywhg3: 1ywh G:189-276 [145936]
  automated match to d1ywha3
  complexed with nag, ndg, so4
13. Domain d1ywhi1: 1ywh I:92-188 [145937]
  automated match to d1ywha1
  complexed with nag, ndg, so4
14. Domain d1ywhi2: 1ywh I:1-82 [145938]
  automated match to d1ywha2
  complexed with nag, ndg, so4
15. Domain d1ywhi3: 1ywh I:189-275 [145939]
  automated match to d1ywha3
  complexed with nag, ndg, so4
16. Domain d1ywhk1: 1ywh K:90-188 [145940]
  automated match to d1ywha1
  complexed with nag, ndg, so4
17. Domain d1ywhk2: 1ywh K:1-78 [145941]
  automated match to d1ywha2
  complexed with nag, ndg, so4
18. Domain d1ywhk3: 1ywh K:189-276 [145942]
  automated match to d1ywha3
  complexed with nag, ndg, so4
19. Domain d1ywhm1: 1ywh M:89-188 [145943]
  automated match to d1ywha1
  complexed with nag, ndg, so4
20. Domain d1ywhm2: 1ywh M:1-81 [145944]
  automated match to d1ywha2
  complexed with nag, ndg, so4
21. Domain d1ywhm3: 1ywh M:189-277 [145945]
  automated match to d1ywha3
  complexed with nag, ndg, so4
22. Domain d1ywho1: 1ywh O:92-188 [145946]
  automated match to d1ywha1
  complexed with nag, ndg, so4
23. Domain d1ywho2: 1ywh O:1-81 [145947]
  automated match to d1ywha2
  complexed with nag, ndg, so4
24. Domain d1ywho3: 1ywh O:189-276 [145948]
  automated match to d1ywha3
  complexed with nag, ndg, so4
Domains for 2fd6:
1. Domain d2fd6u1: 2fd6 U:1-80 [145159]
  Other proteins in same PDB: d2fd6a1, d2fd6a2, d2fd6h1, d2fd6h2, d2fd6l1, d2fd6l2
  complexed with edo, etx, nag, ndg, pg4, pge, so4
2. Domain d2fd6u2: 2fd6 U:189-275 [145160]
  Other proteins in same PDB: d2fd6a1, d2fd6a2, d2fd6h1, d2fd6h2, d2fd6l1, d2fd6l2
  complexed with edo, etx, nag, ndg, pg4, pge, so4
3. Domain d2fd6u3: 2fd6 U:92-188 [145161]
  Other proteins in same PDB: d2fd6a1, d2fd6a2, d2fd6h1, d2fd6h2, d2fd6l1, d2fd6l2
  complexed with edo, etx, nag, ndg, pg4, pge, so4

Domains for 2i9b:

Domain d2i9be1: 2i9b E:188-277 [145508]
Other proteins in same PDB: d2i9ba1, d2i9ba2, d2i9bb1, d2i9bb2, d2i9bc1, d2i9bc2, d2i9bd1, d2i9bd2, d2i9be4, d2i9bf4
complexed with bma, nag, so4
Domain d2i9be2: 2i9b E:1-86 [145509]
Other proteins in same PDB: d2i9ba1, d2i9ba2, d2i9bb1, d2i9bb2, d2i9bc1, d2i9bc2, d2i9bd1, d2i9bd2, d2i9be4, d2i9bf4
complexed with bma, nag, so4
Domain d2i9be3: 2i9b E:87-187 [145510]
Other proteins in same PDB: d2i9ba1, d2i9ba2, d2i9bb1, d2i9bb2, d2i9bc1, d2i9bc2, d2i9bd1, d2i9bd2, d2i9be4, d2i9bf4
complexed with bma, nag, so4

Domain d2i9bf1: 2i9b F:188-277 [145511]
Other proteins in same PDB: d2i9ba1, d2i9ba2, d2i9bb1, d2i9bb2, d2i9bc1, d2i9bc2, d2i9bd1, d2i9bd2, d2i9be4, d2i9bf4
automated match to d2i9be1
complexed with bma, nag, so4

Domain d2i9bf2: 2i9b F:1-86 [145512]
Other proteins in same PDB: d2i9ba1, d2i9ba2, d2i9bb1, d2i9bb2, d2i9bc1, d2i9bc2, d2i9bd1, d2i9bd2, d2i9be4, d2i9bf4
automated match to d2i9be2
complexed with bma, nag, so4

Domain d2i9bf3: 2i9b F:87-187 [145513]
Other proteins in same PDB: d2i9ba1, d2i9ba2, d2i9bb1, d2i9bb2, d2i9bc1, d2i9bc2, d2i9bd1, d2i9bd2, d2i9be4, d2i9bf4
automated match to d2i9be3
complexed with bma, nag, so4

Domain d2i9bg1: 2i9b G:188-277 [145514]
Other proteins in same PDB: d2i9ba1, d2i9ba2, d2i9bb1, d2i9bb2, d2i9bc1, d2i9bc2, d2i9bd1, d2i9bd2, d2i9be4, d2i9bf4
automated match to d2i9be1
complexed with bma, nag, so4

Domain d2i9bg2: 2i9b G:1-82 [145515]
Other proteins in same PDB: d2i9ba1, d2i9ba2, d2i9bb1, d2i9bb2, d2i9bc1, d2i9bc2, d2i9bd1, d2i9bd2, d2i9be4, d2i9bf4
automated match to d2i9be2
complexed with bma, nag, so4

Domain d2i9bg3: 2i9b G:94-187 [145516]
Other proteins in same PDB: d2i9ba1, d2i9ba2, d2i9bb1, d2i9bb2, d2i9bc1, d2i9bc2, d2i9bd1, d2i9bd2, d2i9be4, d2i9bf4
automated match to d2i9be3
complexed with bma, nag, so4

Domain d2i9bh1: 2i9b H:188-277 [145517]
Other proteins in same PDB: d2i9ba1, d2i9ba2, d2i9bb1, d2i9bb2, d2i9bc1, d2i9bc2, d2i9bd1, d2i9bd2, d2i9be4, d2i9bf4
automated match to d2i9be1
complexed with bma, nag, so4

Domain d2i9bh2: 2i9b H:1-82 [145518]
Other proteins in same PDB: d2i9ba1, d2i9ba2, d2i9bb1, d2i9bb2, d2i9bc1, d2i9bc2, d2i9bd1, d2i9bd2, d2i9be4, d2i9bf4
automated match to d2i9be2
complexed with bma, nag, so4

Domain d2i9bh3: 2i9b H:94-187 [145519]
Other proteins in same PDB: d2i9ba1, d2i9ba2, d2i9bb1, d2i9bb2, d2i9bc1, d2i9bc2, d2i9bd1, d2i9bd2, d2i9be4, d2i9bf4
automated match to d2i9be3
complexed with bma, nag, so4

Domains for 3bt1:
1. Domain d3bt1u1: 3bt1 U:1-86 [155537]
  Other proteins in same PDB: d3bt1a1, d3bt1a2, d3bt1b_
  automated match to d2i9be2
  complexed with nag
2. Domain d3bt1u2: 3bt1 U:188-275 [155538]
  Other proteins in same PDB: d3bt1a1, d3bt1a2, d3bt1b_
  automated match to d2i9be1
  complexed with nag
3. Domain d3bt1u3: 3bt1 U:87-187 [155539]
  Other proteins in same PDB: d3bt1a1, d3bt1a2, d3bt1b_
  automated match to d2i9be3
  complexed with nag
Domains for 3bt2:
1. Domain d3bt2u1: 3bt2 U:1A-80 [155547]
  Other proteins in same PDB: d3bt2a1, d3bt2a2, d3bt2b_, d3bt2h1, d3bt2h2, d3bt2l1, d3bt2l2
  automated match to d2i9be2
  complexed with nag
2. Domain d3bt2u2: 3bt2 U:188-275 [155548]
  Other proteins in same PDB: d3bt2a1, d3bt2a2, d3bt2b_, d3bt2h1, d3bt2h2, d3bt2l1, d3bt2l2
  automated match to d2i9be1
  complexed with nag
3. Domain d3bt2u3: 3bt2 U:87-187 [155549]
  Other proteins in same PDB: d3bt2a1, d3bt2a2, d3bt2b_, d3bt2h1, d3bt2h2, d3bt2l1, d3bt2l2
  automated match to d2i9be3
  complexed with nag
Domains for 4qti:
1. Domain d4qtiu1: 4qti U:1-80 [269327]
  Other proteins in same PDB: d4qtil1, d4qtil2
  automated match to d2i9be2
2. Domain d4qtiu2: 4qti U:88-187 [269328]
  Other proteins in same PDB: d4qtil1, d4qtil2
  automated match to d2i9be3
3. Domain d4qtiu3: 4qti U:188-277 [269329]
  Other proteins in same PDB: d4qtil1, d4qtil2
  automated match to d2i9be1

More info for Protein Urokinase plasminogen activator surface receptor uPAR from g.7.1.3: Extracellular domain of cell surface receptors

Timeline for Protein Urokinase plasminogen activator surface receptor uPAR from g.7.1.3: Extracellular domain of cell surface receptors:

Protein Urokinase plasminogen activator surface receptor uPAR from g.7.1.3: Extracellular domain of cell surface receptors first appeared in SCOP 1.75
Protein Urokinase plasminogen activator surface receptor uPAR from g.7.1.3: Extracellular domain of cell surface receptors appears in SCOPe 2.06
Protein Urokinase plasminogen activator surface receptor uPAR from g.7.1.3: Extracellular domain of cell surface receptors appears in the current release, SCOPe 2.08