SCOPe 2.03: Species: Human (Homo sapiens) [TaxId: 9606]

Root: SCOPe 2.03
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (8 families)
Family c.3.1.2: FAD-linked reductases, N-terminal domain [51913] (18 proteins)
C-terminal domain is alpha+beta is common for the family
Protein Lysine-specific histone demethylase 1, LSD1 [159432] (1 species)
Species Human (Homo sapiens) [TaxId:9606] [159433] (8 PDB entries)
Uniprot O60341 274-654,764-836

Domain(s) for 2dw4:
- Domain d2dw4a2: 2dw4 A:274-654,A:764-831 [146595]
  Other proteins in same PDB: d2dw4a1, d2dw4a3
  automatically matched to 2IW5 A:274-654,A:764-836
  complexed with fad
Domain(s) for 2ejr:
- Domain d2ejra2: 2ejr A:274-654,A:764-831 [146878]
  Other proteins in same PDB: d2ejra1, d2ejra3
  automatically matched to 2IW5 A:274-654,A:764-836
  complexed with f2n
Domain(s) for 2h94:
- Domain d2h94a2: 2h94 A:274-654,A:764-835 [147246]
  Other proteins in same PDB: d2h94a1, d2h94a3
  automatically matched to 2IW5 A:274-654,A:764-836
  complexed with fad, hg

Domain(s) for 2iw5:

Domain d2iw5a2: 2iw5 A:274-654,A:764-836 [145540]
Other proteins in same PDB: d2iw5a1, d2iw5a3, d2iw5b1
includes the CoREST-binding subdomain (420-520), a long alpha-helical hairpin
complexed with cl, fad, gol, nh4

Domain(s) for 2uxn:
- Domain d2uxna2: 2uxn A:274-654,A:764-836 [145761]
  Other proteins in same PDB: d2uxna1, d2uxna3, d2uxnb1
  automatically matched to 2IW5 A:274-654,A:764-836
  complexed with cl, fda, gol
Domain(s) for 2uxx:
- Domain d2uxxa2: 2uxx A:274-654,A:764-835 [152311]
  Other proteins in same PDB: d2uxxa1, d2uxxa3
  automated match to d2iw5a2
  complexed with cl, faj, gol
Domain(s) for 2z3y:
- Domain d2z3ya2: 2z3y A:274-654,A:764-831 [154025]
  Other proteins in same PDB: d2z3ya1, d2z3ya3
  automatically matched to 2IW5 A:274-654,A:764-836
  complexed with f2n
Domain(s) for 2z5u:
- Domain d2z5ua2: 2z5u A:274-654,A:764-831 [154168]
  Other proteins in same PDB: d2z5ua1, d2z5ua3
  automatically matched to 2IW5 A:274-654,A:764-836
  complexed with faj

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.3.1.2 Lysine-specific histone demethylase 1, LSD1:

Species Human (Homo sapiens) [TaxId:9606] from c.3.1.2 Lysine-specific histone demethylase 1, LSD1 first appeared in SCOP 1.75
Species Human (Homo sapiens) [TaxId:9606] from c.3.1.2 Lysine-specific histone demethylase 1, LSD1 appears in SCOPe 2.02
Species Human (Homo sapiens) [TaxId:9606] from c.3.1.2 Lysine-specific histone demethylase 1, LSD1 appears in SCOPe 2.04
Species Human (Homo sapiens) [TaxId:9606] from c.3.1.2 Lysine-specific histone demethylase 1, LSD1 appears in the current release, SCOPe 2.08