Lineage for Family a.43.1.10: VirC2-like

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.43: Ribbon-helix-helix [47597] (1 superfamily) core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.43.1: Ribbon-helix-helix [47598] (12 families) formerly Met repressor-like; dimeric proteins; the N-termini form a small beta-sheet ribbon

5. Family a.43.1.10: VirC2-like [158482] (1 protein) Pfam PF07181; duplicated ribbon-helix-helix motif; fold forms a trefoil knot