SCOPe 2.05: Domain d3dylb_: 3dyl B:

Lineage for d3dylb_ (3dyl B:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.2: PDEase [48548] (7 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A [109942] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [109943] (19 PDB entries)
   Uniprot O76083 241-566

8. Domain d3dylb_: 3dyl B: [157941]
   automated match to d2hd1a1
   complexed with fmt, ibm, mg, mn, pcg

Details for d3dylb_

PDB Entry: 3dyl, 2.7 Å

PDB Description: human phosphdiesterase 9 substrate complex (ES complex)

PDB Compounds: (B:) human phosphodiesterase 9

SCOPe Domain Sequences for d3dylb_:

Sequence; same for both SEQRES and ATOM records:

>d3dylb_ a.211.1.2 (B:) High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A {Human (Homo sapiens) [TaxId: 9606]}
gshmtypkyllspetiealrkptfdvwlwepnemlsclehmyhdlglvrdfsinpvtlrr
wlfcvhdnyrnnpfhnfrhcfcvaqmmysmvwlcslqekfsqtdililmtaaichdldhp
gynntyqinartelavryndisplenhhcavafqilaepecnifsnippdgfkqirqgmi
tlilatdmarhaeimdsfkekmenfdysneehmtllkmilikccdisnevrpmevaepwv
dclleeyfmqsdrekseglpvapfmdrdkvtkataqigfikfvlipmfetvtklfpmvee
imlqplwesrdryeelkriddamkelqk

Timeline for d3dylb_:

• d3dylb_ first appeared in SCOP 1.75, called d3dylb1
  
• d3dylb_ appears in SCOPe 2.04
  
• d3dylb_ is called d3dylb2 in SCOPe 2.06
  
• d3dylb_ appears in the current release, SCOPe 2.08, called d3dylb2