SCOP 1.75: Domain d3dy8a1: 3dy8 A:182-505

Lineage for d3dy8a1 (3dy8 A:182-505)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (5 families)

5. Family a.211.1.2: PDEase [48548] (6 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A [109942] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [109943] (7 PDB entries)
   Uniprot O76083 241-566

8. Domain d3dy8a1: 3dy8 A:182-505 [157937]
   automatically matched to d2hd1a1
   complexed with 5gp, fmt, ibm, mg, mn

Details for d3dy8a1

PDB Entry: 3dy8, 2.15 Å

PDB Description: Human Phosphodiesterase 9 in complex with product 5'-GMP (E+P complex)

PDB Compounds: (A:) human phosphodiesterase 9

SCOP Domain Sequences for d3dy8a1:

Sequence; same for both SEQRES and ATOM records:

>d3dy8a1 a.211.1.2 (A:182-505) High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A {Human (Homo sapiens) [TaxId: 9606]}
typkyllspetiealrkptfdvwlwepnemlsclehmyhdlglvrdfsinpvtlrrwlfc
vhdnyrnnpfhnfrhcfcvaqmmysmvwlcslqekfsqtdililmtaaichdldhpgynn
tyqinartelavryndisplenhhcavafqilaepecnifsnippdgfkqirqgmitlil
atdmarhaeimdsfkekmenfdysneehmtllkmilikccdisnevrpmevaepwvdcll
eeyfmqsdrekseglpvapfmdrdkvtkataqigfikfvlipmfetvtklfpmveeimlq
plwesrdryeelkriddamkelqk

Timeline for d3dy8a1:

• d3dy8a1 is new in SCOP 1.75
  
• d3dy8a1 is called d3dy8a_ in SCOPe 2.01
  
• d3dy8a1 appears in the current release, SCOPe 2.08, called d3dy8a2