SCOP 1.75: Domain d3dwha1: 3dwh A:414-614

Lineage for d3dwha1 (3dwh A:414-614)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.122: PUA domain-like [88696] (1 superfamily)
   pseudobarrel; mixed folded sheet of 5 strands; order 13452; strand 1 and 3 are parallel to each other

4. Superfamily b.122.1: PUA domain-like [88697] (13 families)

5. Family b.122.1.12: SRA domain-like [159368] (1 protein)
   Pfam PF02182; recognizes the modified cytosine base (m5C) by flipping it out of DNA

6. Protein E3 ubiquitin-protein ligase UHRF1 [159369] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [159370] (4 PDB entries)
   Uniprot Q96T88 409-615! Uniprot Q96T88 414-617

8. Domain d3dwha1: 3dwh A:414-614 [157912]
   automatically matched to 3BI7 A:414-617
   complexed with gol, so4

Details for d3dwha1

PDB Entry: 3dwh, 1.95 Å

PDB Description: Structural and Functional Analysis of SRA domain

PDB Compounds: (A:) E3 ubiquitin-protein ligase UHRF1

SCOP Domain Sequences for d3dwha1:

Sequence, based on SEQRES records:

>d3dwha1 b.122.1.12 (A:414-614) E3 ubiquitin-protein ligase UHRF1 {Human (Homo sapiens) [TaxId: 9606]}
psnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdhg
nfftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkpv
rvvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtke
gkdrikklgltmqypegylea

Sequence, based on observed residues (ATOM records):

>d3dwha1 b.122.1.12 (A:414-614) E3 ubiquitin-protein ligase UHRF1 {Human (Homo sapiens) [TaxId: 9606]}
psnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdhg
nfftytgsggscdqkltntnralalncfapindqegaeakdwrsgkpvrvvrnvkggkns
kyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtkegkdrikklgltm
qypegylea

Timeline for d3dwha1:

• d3dwha1 is new in SCOP 1.75
  
• d3dwha1 is called d3dwha_ in SCOPe 2.01
  
• d3dwha1 appears in the current release, SCOPe 2.08, called d3dwha2