SCOPe 2.08: Domain d3dw8c_: 3dw8 C:

Lineage for d3dw8c_ (3dw8 C:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.159: Metallo-dependent phosphatases [56299] (1 superfamily)
   4 layers: alpha/beta/beta/alpha; mixed beta sheets; contains duplication

4. Superfamily d.159.1: Metallo-dependent phosphatases [56300] (13 families)
   different families of this superfamily are groupped in a single Pfam family, Pfam PF00149

5. Family d.159.1.3: Protein serine/threonine phosphatase [56310] (6 proteins)

6. Protein Protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha [143933] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [143934] (12 PDB entries)
   Uniprot P67775 2-294

8. Domain d3dw8c_: 3dw8 C: [157909]
   Other proteins in same PDB: d3dw8a2, d3dw8a3, d3dw8d2, d3dw8d3
   automated match to d2nylc1
   complexed with mn

Details for d3dw8c_

PDB Entry: 3dw8, 2.85 Å

PDB Description: structure of a protein phosphatase 2a holoenzyme with b55 subunit

PDB Compounds: (C:) Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

SCOPe Domain Sequences for d3dw8c_:

Sequence; same for both SEQRES and ATOM records:

>d3dw8c_ d.159.1.3 (C:) Protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha {Human (Homo sapiens) [TaxId: 9606]}
ftkeldqwieqlneckqlsesqvkslcekakeiltkesnvqevrcpvtvcgdvhgqfhdl
melfriggkspdtnylfmgdyvdrgyysvetvtllvalkvryreritilrgnhesrqitq
vygfydeclrkygnanvwkyftdlfdylpltalvdgqifclhgglspsidtldhiraldr
lqevphegpmcdllwsdpddrggwgisprgagytfgqdisetfnhangltlvsrahqlvm
egynwchdrnvvtifsapnycyrcgnqaaimelddtlkysflqfdpap

Timeline for d3dw8c_:

• d3dw8c_ first appeared in SCOP 1.75, called d3dw8c1
  
• d3dw8c_ appears in SCOPe 2.07