SCOPe 2.08: Domain d3dw8a2: 3dw8 A:9-589

Lineage for d3dw8a2 (3dw8 A:9-589)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (28 families)

5. Family a.118.1.2: HEAT repeat [48385] (3 proteins)
   Pfam PF02985
   this is a repeat family; one repeat unit is 1b3u A:295-335 found in domain

6. Protein Constant regulatory domain of protein phosphatase 2a, pr65alpha [48386] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48387] (12 PDB entries)

8. Domain d3dw8a2: 3dw8 A:9-589 [157908]
   Other proteins in same PDB: d3dw8a3, d3dw8c_, d3dw8d3, d3dw8f_
   automated match to d1b3ua_
   complexed with mn

Details for d3dw8a2

PDB Entry: 3dw8, 2.85 Å

PDB Description: structure of a protein phosphatase 2a holoenzyme with b55 subunit

PDB Compounds: (A:) Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

SCOPe Domain Sequences for d3dw8a2:

Sequence; same for both SEQRES and ATOM records:

>d3dw8a2 a.118.1.2 (A:9-589) Constant regulatory domain of protein phosphatase 2a, pr65alpha {Human (Homo sapiens) [TaxId: 9606]}
slypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiydedevlla
laeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehspsdleahf
vplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpmvrraaask
lgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedlealvmptl
rqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevraaashkvke
fcenlsadcrenvimsqilpcikelvsdanqhvksalasvimglspilgkdntiehllpl
flaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvrlaiieymp
llagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewahatiipkvla
msgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnvakslqkig
pildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla

Timeline for d3dw8a2:

• d3dw8a2 first appeared in SCOP 1.75, called d3dw8a1
  
• d3dw8a2 appears in SCOPe 2.07