SCOPe 2.07: Domain d3dt3b_: 3dt3 B:

Lineage for d3dt3b_ (3dt3 B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (82 PDB entries)
   Uniprot P03372 307-551

8. Domain d3dt3b_: 3dt3 B: [157849]
   automated match to d1qkua_
   complexed with 369

Details for d3dt3b_

PDB Entry: 3dt3, 2.4 Å

PDB Description: human estrogen receptor alpha lbd with gw368

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d3dt3b_:

Sequence, based on SEQRES records:

>d3dt3b_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemld
ahr

Sequence, based on observed residues (ATOM records):

>d3dt3b_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytfstlksleekdhihrvldkitdtli
hlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcnvvplydlllemldahr

Timeline for d3dt3b_:

• d3dt3b_ first appeared in SCOP 1.75, called d3dt3b1
  
• d3dt3b_ appears in SCOPe 2.06
  
• d3dt3b_ appears in the current release, SCOPe 2.08