SCOPe 2.01: Domain d3dlqi_: 3dlq I:

Lineage for d3dlqi_ (3dlq I:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.26: 4-helical cytokines [47265] (1 superfamily)
   core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections

4. Superfamily a.26.1: 4-helical cytokines [47266] (3 families)
   there are two different topoisomers of this fold with different entanglements of the two crossover connections

5. Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 proteins)
   contains an additional helix in one of the crossover connections

6. Protein Interleukin-22 (IL-22) [89036] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89037] (5 PDB entries)

8. Domain d3dlqi_: 3dlq I: [157802]
   automated match to d1m4ra_

Details for d3dlqi_

PDB Entry: 3dlq, 1.9 Å

PDB Description: crystal structure of the il-22/il-22r1 complex

PDB Compounds: (I:) Interleukin-22

SCOPe Domain Sequences for d3dlqi_:

Sequence, based on SEQRES records:

>d3dlqi_ a.26.1.3 (I:) Interleukin-22 (IL-22) {Human (Homo sapiens) [TaxId: 9606]}
arldksnfqqpyitnrtfmlakeasladnntdvrligeklfhgvsmsercylmkqvlnft
leevlfpqsdrfqpymqevvpflarlsnrlstchiegddlhiqrnvqklkdtvkklgesg
eikaigeldllfmslrnaci

Sequence, based on observed residues (ATOM records):

>d3dlqi_ a.26.1.3 (I:) Interleukin-22 (IL-22) {Human (Homo sapiens) [TaxId: 9606]}
arldksnfqqpyitnrtfmlakeasladnntdvrligeklfhgvsmsercylmkqvlnft
leevlfpqsdrfqpymqevvpflarlsnrlshiqrnvqklkdtvkklgesgeikaigeld
llfmslrnaci

Timeline for d3dlqi_:

• d3dlqi_ first appeared in SCOP 1.75, called d3dlqi1
  
• d3dlqi_ appears in SCOPe 2.02
  
• d3dlqi_ appears in the current release, SCOPe 2.08