SCOP 1.75: Domain d3dekd1: 3dek D:34-277

Lineage for d3dekd1 (3dek D:34-277)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (2 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (7 proteins)

6. Protein Apopain (caspase-3, cpp32) [52131] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52132] (19 PDB entries)

8. Domain d3dekd1: 3dek D:34-277 [157591]
   automatically matched to d1nmqa_
   complexed with rxd

Details for d3dekd1

PDB Entry: 3dek, 2.4 Å

PDB Description: crystal structures of caspase-3 with bound isoquinoline-1,3,4-trione derivative inhibitors

PDB Compounds: (D:) Caspase-3

SCOP Domain Sequences for d3dekd1:

Sequence, based on SEQRES records:

>d3dekd1 c.17.1.1 (D:34-277) Apopain (caspase-3, cpp32) {Human (Homo sapiens) [TaxId: 9606]}
dnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndltr
eeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsltg
kpklfiiqacrgteldcgietdsgvdddmachkipvdadflyaystapgyyswrnskdgs
wfiqslcamlkqyadklefmhiltrvnrkvatefesfsfdatfhakkqipcivsmltkel
yfyh

Sequence, based on observed residues (ATOM records):

>d3dekd1 c.17.1.1 (D:34-277) Apopain (caspase-3, cpp32) {Human (Homo sapiens) [TaxId: 9606]}
dnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndltr
eeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsltg
kpklfiiqacrgteldcgiehkipvdadflyaystapgyyswrnskdgswfiqslcamlk
qyadklefmhiltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfyh

Timeline for d3dekd1:

• d3dekd1 is new in SCOP 1.75
  
• d3dekd1 is called d3dekd_ in SCOPe 2.01
  
• d3dekd1 appears in the current release, SCOPe 2.08, called d3dekd_