SCOPe 2.08: Domain d3d7ua1: 3d7u A:188-448

Lineage for d3d7ua1 (3d7u A:188-448)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Carboxyl-terminal src kinase (csk) [56164] (1 species)
   PTK group; CSK subfamily; non-membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56165] (4 PDB entries)

8. Domain d3d7ua1: 3d7u A:188-448 [157432]
   automatically matched to d1byga_

Details for d3d7ua1

PDB Entry: 3d7u, 4.11 Å

PDB Description: Structural basis for the recognition of c-Src by its inactivator Csk

PDB Compounds: (A:) Tyrosine-protein kinase CSK

SCOPe Domain Sequences for d3d7ua1:

Sequence, based on SEQRES records:

>d3d7ua1 d.144.1.7 (A:188-448) Carboxyl-terminal src kinase (csk) {Human (Homo sapiens) [TaxId: 9606]}
walnmkelkllqtigkgefgdvmlgdyrgnkvavkcikndataqaflaeasvmtqlrhsn
lvqllgviveekgglyivteymakgslvdylrsrgrsvlggdcllkfsldvceameyleg
nnfvhrdlaarnvlvsednvakvsdfgltkeasstqdtgklpvkwtapealrekkfstks
dvwsfgillweiysfgrvpypriplkdvvprvekgykmdapdgcppavyevmkncwhlda
amrpsflqlreqlehikthel

Sequence, based on observed residues (ATOM records):

>d3d7ua1 d.144.1.7 (A:188-448) Carboxyl-terminal src kinase (csk) {Human (Homo sapiens) [TaxId: 9606]}
walnmkelkllqtigkgefgdvmlgdyrgnkvavkcikndataqaflaeasvmtqlrhsn
lvqllgviveekgglyivteymakgslvdylrsrgrsvlggdcllkfsldvceameyleg
nnfvhrdlaarnvlvsednvakvsdfgltkeasklpvkwtapealrekkfstksdvwsfg
illweiysfgrvpypriplkdvvprvekgykmdapdgcppavyevmkncwhldaamrpsf
lqlreqlehikthel

Timeline for d3d7ua1:

• d3d7ua1 first appeared in SCOP 1.75
  
• d3d7ua1 appears in SCOPe 2.07