Lineage for d3d62a_ (3d62 A:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2794584Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2794585Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2797303Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (5 proteins)
  6. 2797364Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (8 species)
    contains an extra alpha-helical domain
  7. 2797397Species SARS coronavirus [TaxId:227859] [89349] (86 PDB entries)
  8. 2797510Domain d3d62a_: 3d62 A: [157411]
    automated match to d1q2wb_
    complexed with 959

    has additional subdomain(s) that are not in the common domain

Details for d3d62a_

PDB Entry: 3d62 (more details), 2.7 Å

PDB Description: development of broad-spectrum halomethyl ketone inhibitors against coronavirus main protease 3clpro
PDB Compounds: (A:) 3C-like proteinase

SCOPe Domain Sequences for d3d62a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3d62a_ b.47.1.4 (A:) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {SARS coronavirus [TaxId: 227859]}
frkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllirks
nhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyngsp
sgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegkfy
gpfvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynyepl
tqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqcs

SCOPe Domain Coordinates for d3d62a_:

Click to download the PDB-style file with coordinates for d3d62a_.
(The format of our PDB-style files is described here.)

Timeline for d3d62a_: