SCOPe 2.03: Domain d3d24a1: 3d24 A:194-420

Lineage for d3d24a1 (3d24 A:194-420)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Steroid hormone receptor ERR1 [109990] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [109991] (3 PDB entries)
   Uniprot P11474 289-516

8. Domain d3d24a1: 3d24 A:194-420 [157216]
   automatically matched to d1xb7a_
   protein/DNA complex; protein/RNA complex

Details for d3d24a1

PDB Entry: 3d24, 2.11 Å

PDB Description: Crystal structure of ligand-binding domain of estrogen-related receptor alpha (ERRalpha) in complex with the peroxisome proliferators-activated receptor coactivator-1alpha box3 peptide (PGC-1alpha)

PDB Compounds: (A:) Steroid hormone receptor ERR1

SCOPe Domain Sequences for d3d24a1:

Sequence, based on SEQRES records:

>d3d24a1 a.123.1.1 (A:194-420) Steroid hormone receptor ERR1 {Human (Homo sapiens) [TaxId: 9606]}
vnalvshllvvepeklyampdpagpdghlpavatlcdlfdreivvtiswaksipgfssls
lsdqmsvlqsvwmevlvlgvaqrslplqdelafaedlvldeegaraaglgelgaallqlv
rrlqalrlereeyvllkalalansdsvhiedaeaveqlrealhealleyeagragpggga
errragrllltlpllrqtagkvlahfygvklegkvpmhklflemlea

Sequence, based on observed residues (ATOM records):

>d3d24a1 a.123.1.1 (A:194-420) Steroid hormone receptor ERR1 {Human (Homo sapiens) [TaxId: 9606]}
vnalvshllvvepeklyampavatlcdlfdreivvtiswaksipgfsslslsdqmsvlqs
vwmevlvlgvaqrslplqdelafaedlvldeegaraaglgelgaallqlvrrlqalrler
eeyvllkalalansdsvhiedaeaveqlrealhealleyeagerrragrllltlpllrqt
agkvlahfygvklegkvpmhklflemlea

Timeline for d3d24a1:

• d3d24a1 first appeared in SCOP 1.75
  
• d3d24a1 appears in SCOPe 2.02
  
• d3d24a1 appears in SCOPe 2.04
  
• d3d24a1 appears in the current release, SCOPe 2.08