SCOPe 2.08: Domain d3cu0b2: 3cu0 B:76-335

Lineage for d3cu0b2 (3cu0 B:76-335)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.68: Nucleotide-diphospho-sugar transferases [53447] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214657; strand 6 is antiparallel to the rest

4. Superfamily c.68.1: Nucleotide-diphospho-sugar transferases [53448] (20 families)

5. Family c.68.1.7: 1,3-glucuronyltransferase [53467] (3 proteins)
   automatically mapped to Pfam PF03360

6. Protein 1,3-Glucuronyltransferase I (glcAT-I) [53468] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [53469] (3 PDB entries)

8. Domain d3cu0b2: 3cu0 B:76-335 [156987]
   Other proteins in same PDB: d3cu0a3, d3cu0b3
   complexed with mn, so4, udp

Details for d3cu0b2

PDB Entry: 3cu0, 1.9 Å

PDB Description: human beta 1,3-glucuronyltransferase i (glcat-i) in complex with udp and gal-gal(6-so4)-xyl(2-po4)-o-ser

PDB Compounds: (B:) Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

SCOPe Domain Sequences for d3cu0b2:

Sequence, based on SEQRES records:

>d3cu0b2 c.68.1.7 (B:76-335) 1,3-Glucuronyltransferase I (glcAT-I) {Human (Homo sapiens) [TaxId: 9606]}
tiyvvtptyarlvqkaelvrlsqtlslvprlhwllvedaegptplvsgllaasgllfthl
vvltpkaqrlregepgwvhprgveqrnkaldwlrgrggavggekdppppgtqgvvyfadd
dntysrelfeemrwtrgvsvwpvglvgglrfegpqvqdgrvvgfhtawepsrpfpvdmag
favalpllldkpnaqfdstaprghlessllshlvdpkdlepraanctrvlvwhtrtekpk
mkqeeqlqrqgrgsdpaiev

Sequence, based on observed residues (ATOM records):

>d3cu0b2 c.68.1.7 (B:76-335) 1,3-Glucuronyltransferase I (glcAT-I) {Human (Homo sapiens) [TaxId: 9606]}
tiyvvtptyarlvqkaelvrlsqtlslvprlhwllvedaegptplvsgllaasgllfthl
vvltpprgveqrnkaldwlrgrggavggekdppppgtqgvvyfadddntysrelfeemrw
trgvsvwpvglvgglrfegpqvqdgrvvgfhtawepsrpfpvdmagfavalpllldkpna
qfdstaprghlessllshlvdpkdlepraanctrvlvwhtrtekpkmkqeeqlqrqgrgs
dpaiev

Timeline for d3cu0b2:

• d3cu0b2 first appeared in SCOP 1.75, called d3cu0b1
  
• d3cu0b2 appears in SCOPe 2.07