SCOPe 2.07: Domain d3cs8a2: 3cs8 A:206-476

Lineage for d3cs8a2 (3cs8 A:206-476)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (212 PDB entries)

8. Domain d3cs8a2: 3cs8 A:206-476 [156958]
   Other proteins in same PDB: d3cs8a3
   automated match to d1knua_
   complexed with brl, so4

Details for d3cs8a2

PDB Entry: 3cs8, 2.3 Å

PDB Description: Structural and Biochemical Basis for the Binding Selectivity of PPARg to PGC-1a

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3cs8a2:

Sequence, based on SEQRES records:

>d3cs8a2 a.123.1.1 (A:206-476) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfk
hitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvhei
iytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdla
ifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqi
vtehvqllqvikktetdmslhpllqeiykdl

Sequence, based on observed residues (ATOM records):

>d3cs8a2 a.123.1.1 (A:206-476) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkiplq
eqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmla
slmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiavi
ilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvq
llqvikktetdmslhpllqeiykdl

Timeline for d3cs8a2:

• d3cs8a2 first appeared in SCOP 1.75, called d3cs8a1
  
• d3cs8a2 appears in SCOPe 2.06
  
• d3cs8a2 appears in the current release, SCOPe 2.08