SCOP 1.75: Domain d3cs8a1: 3cs8 A:206-476

Lineage for d3cs8a1 (3cs8 A:206-476)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (46 PDB entries)
   Uniprot P37231 232-505

8. Domain d3cs8a1: 3cs8 A:206-476 [156958]
   automatically matched to d1wm0x_
   complexed with brl, so4

Details for d3cs8a1

PDB Entry: 3cs8, 2.3 Å

PDB Description: Structural and Biochemical Basis for the Binding Selectivity of PPARg to PGC-1a

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOP Domain Sequences for d3cs8a1:

Sequence, based on SEQRES records:

>d3cs8a1 a.123.1.1 (A:206-476) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
pesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfk
hitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvhei
iytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdla
ifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqi
vtehvqllqvikktetdmslhpllqeiykdl

Sequence, based on observed residues (ATOM records):

>d3cs8a1 a.123.1.1 (A:206-476) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
pesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkiplq
eqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmla
slmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiavi
ilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvq
llqvikktetdmslhpllqeiykdl

Timeline for d3cs8a1:

• d3cs8a1 is new in SCOP 1.75
  
• d3cs8a1 is called d3cs8a_ in SCOPe 2.01
  
• d3cs8a1 appears in the current release, SCOPe 2.08, called d3cs8a2