SCOPe 2.07: Domain d3cs7a_: 3cs7 A:

Lineage for d3cs7a_ (3cs7 A:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein automated matches [190044] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187233] (166 PDB entries)

8. Domain d3cs7a_: 3cs7 A: [156956]
   Other proteins in same PDB: d3cs7l_
   automated match to d1c5md_
   complexed with ca, lg0

Details for d3cs7a_

PDB Entry: 3cs7, 2.2 Å

PDB Description: factor xa in complex with the inhibitor 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one

PDB Compounds: (A:) coagulation factor x

SCOPe Domain Sequences for d3cs7a_:

Sequence; same for both SEQRES and ATOM records:

>d3cs7a_ b.47.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

Timeline for d3cs7a_:

• d3cs7a_ first appeared in SCOP 1.75, called d3cs7a1
  
• d3cs7a_ appears in SCOPe 2.06
  
• d3cs7a_ appears in the current release, SCOPe 2.08