Lineage for d3cica_ (3cic A:)

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 955287Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 955288Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 956278Family b.50.1.2: Pepsin-like [50646] (11 proteins)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 956335Protein beta-secretase (memapsin) [50671] (1 species)
  7. 956336Species Human (Homo sapiens) [TaxId:9606] [50672] (117 PDB entries)
    Uniprot P56817 58-446 ! Uniprot P56817 60-447
  8. 956350Domain d3cica_: 3cic A: [156666]
    automated match to d1fkna_
    complexed with 316, tar

Details for d3cica_

PDB Entry: 3cic (more details), 1.75 Å

PDB Description: structure of bace bound to sch709583
PDB Compounds: (A:) Beta-secretase 1

SCOPe Domain Sequences for d3cica_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3cica_ b.50.1.2 (A:) beta-secretase (memapsin) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3cica_:

Click to download the PDB-style file with coordinates for d3cica_.
(The format of our PDB-style files is described here.)

Timeline for d3cica_: