SCOPe 2.05: Domain d3chsa1: 3chs A:461-610

Lineage for d3chsa1 (3chs A:461-610)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (26 families)

5. Family a.118.1.7: Leukotriene A4 hydrolase C-terminal domain [63608] (1 protein)
   automatically mapped to Pfam PF09127
   this is a repeat family; one repeat unit is 1gw6 A:513-547 found in domain

6. Protein Leukotriene A4 hydrolase C-terminal domain [63609] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63610] (45 PDB entries)
   Uniprot P09960

8. Domain d3chsa1: 3chs A:461-610 [156653]
   Other proteins in same PDB: d3chsa2, d3chsa3
   automated match to d3fh8a3
   complexed with 4bu, imd, yb, zn

Details for d3chsa1

PDB Entry: 3chs, 2.55 Å

PDB Description: crystal structure of leukotriene a4 hydrolase in complex with (2s)-2- amino-5-[[4-[(2s)-2-hydroxy-2-phenyl-ethoxy]phenyl]amino]-5-oxo- pentanoic acid

PDB Compounds: (A:) Leukotriene A-4 hydrolase

SCOPe Domain Sequences for d3chsa1:

Sequence; same for both SEQRES and ATOM records:

>d3chsa1 a.118.1.7 (A:461-610) Leukotriene A4 hydrolase C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
dmtltnacialsqrwitakeddlnsfnatdlkdlsshqlneflaqtlqraplplghikrm
qevynfnainnseirfrwlrlciqskwedaiplalkmateqgrmkftrplfkdlaafdks
hdqavrtyqehkasmhpvtamlvgkdlkvd

Timeline for d3chsa1:

• d3chsa1 first appeared in SCOP 1.75
  
• d3chsa1 appears in SCOPe 2.04
  
• d3chsa1 appears in SCOPe 2.06
  
• d3chsa1 appears in the current release, SCOPe 2.08