SCOPe 2.01: Domain d3ch5a_: 3ch5 A:

Lineage for d3ch5a_ (3ch5 A:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Ran [52609] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52611] (8 PDB entries)

8. Domain d3ch5a_: 3ch5 A: [156620]
   Other proteins in same PDB: d3ch5b_
   automated match to d1byub_
   complexed with gdp, mg, so4, zn

Details for d3ch5a_

PDB Entry: 3ch5, 2.1 Å

PDB Description: The crystal structure of the RanGDP-Nup153ZnF2 complex

PDB Compounds: (A:) GTP-binding nuclear protein ran

SCOPe Domain Sequences for d3ch5a_:

Sequence, based on SEQRES records:

>d3ch5a_ c.37.1.8 (A:) Ran {Human (Homo sapiens) [TaxId: 9606]}
pqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdt
agqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdi
kdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvampalappe
vvmdpalaaqyehdlevaq

Sequence, based on observed residues (ATOM records):

>d3ch5a_ c.37.1.8 (A:) Ran {Human (Homo sapiens) [TaxId: 9606]}
pqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdt
agqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdi
kdrkvkaksinlqyydisaksnynfekpflwlarkligdpnlefvampalappevvmdpa
laaqyehdlevaq

Timeline for d3ch5a_:

• d3ch5a_ first appeared in SCOP 1.75, called d3ch5a1
  
• d3ch5a_ appears in SCOPe 2.02
  
• d3ch5a_ appears in the current release, SCOPe 2.08