Lineage for d3cg2a1 (3cg2 A:4-351)

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 874255Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 874256Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 874317Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 874963Protein MAP kinase p38 [56129] (2 species)
    CMGC group; ERK/MAPK subfamily; serine/threonine kinase
  7. 874964Species Human (Homo sapiens) [TaxId:9606] [56130] (60 PDB entries)
  8. 875027Domain d3cg2a1: 3cg2 A:4-351 [156614]
    automatically matched to d1a9ua_
    complexed with n4d

Details for d3cg2a1

PDB Entry: 3cg2 (more details), 2.15 Å

PDB Description: P38 Alpha Kinase complexed with a Pyrazolo-Pyrimidine based inhibitor
PDB Compounds: (A:) Mitogen-activated protein kinase 14

SCOP Domain Sequences for d3cg2a1:

Sequence, based on SEQRES records: (download)

>d3cg2a1 d.144.1.7 (A:4-351) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyv
atrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpg
aellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqal
ahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpp

Sequence, based on observed residues (ATOM records): (download)

>d3cg2a1 d.144.1.7 (A:4-351) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsvcaafdtktglrvavkklsrpfqsiihakrt
yrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltddhvq
fliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglartrwyrapeimlnqtv
diwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsltq
mpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpddepvadpyd
qsfesrdllidewksltydevisfvpp

SCOP Domain Coordinates for d3cg2a1:

Click to download the PDB-style file with coordinates for d3cg2a1.
(The format of our PDB-style files is described here.)

Timeline for d3cg2a1:

  • d3cg2a1 is new in SCOP 1.75
  • d3cg2a1 does not appear in SCOPe 2.01