SCOPe 2.06: Domain d3cccc1: 3ccc C:41-508

Lineage for d3cccc1 (3ccc C:41-508)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.70: 8-bladed beta-propeller [50997] (3 superfamilies)
   consists of eight 4-stranded beta-sheet motifs; meander
   also found in some members of the WD40-repeat superfamily

4. Superfamily b.70.3: DPP6 N-terminal domain-like [82171] (1 family)
   automatically mapped to Pfam PF00930

5. Family b.70.3.1: DPP6 N-terminal domain-like [82172] (3 proteins)
   Pfam PF00930

6. Protein Dipeptidyl peptidase IV/CD26, N-terminal domain [82173] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82174] (93 PDB entries)
   Uniprot P27487 39-776 ! Uniprot P27487 ! Uniprot P27487

8. Domain d3cccc1: 3ccc C:41-508 [156256]
   Other proteins in same PDB: d3ccca2, d3cccb2, d3cccc2, d3cccd2
   automated match to d1orva1
   complexed with 7ac, nag

Details for d3cccc1

PDB Entry: 3ccc, 2.71 Å

PDB Description: crystal structure of human dpp4 in complex with a benzimidazole derivative

PDB Compounds: (C:) dipeptidyl peptidase 4

SCOPe Domain Sequences for d3cccc1:

Sequence, based on SEQRES records:

>d3cccc1 b.70.3.1 (C:41-508) Dipeptidyl peptidase IV/CD26, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
ktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvflenstfdefgh
sindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtwspv
ghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwspng
tflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslssvt
natsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwncl
varqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfitkg
twevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyysvs
fskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvq

Sequence, based on observed residues (ATOM records):

>d3cccc1 b.70.3.1 (C:41-508) Dipeptidyl peptidase IV/CD26, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
ktytltdylkntyrlklyslrwisdheylykqnilvfnaeygnssvflenstfdefghsi
ndysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtwspvgh
klayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwspngtf
layaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslssvtna
tsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwnclva
rqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfitkgtw
evigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyysvsfs
keakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvq

Timeline for d3cccc1:

• d3cccc1 first appeared in SCOP 1.75
  
• d3cccc1 appears in SCOPe 2.05
  
• d3cccc1 appears in SCOPe 2.07
  
• d3cccc1 appears in the current release, SCOPe 2.08