SCOPe 2.05: Domain d3ccbb1: 3ccb B:36-508

Lineage for d3ccbb1 (3ccb B:36-508)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.70: 8-bladed beta-propeller [50997] (3 superfamilies)
   consists of eight 4-stranded beta-sheet motifs; meander
   also found in some members of the WD40-repeat superfamily

4. Superfamily b.70.3: DPP6 N-terminal domain-like [82171] (1 family)
   automatically mapped to Pfam PF00930

5. Family b.70.3.1: DPP6 N-terminal domain-like [82172] (3 proteins)
   Pfam PF00930

6. Protein Dipeptidyl peptidase IV/CD26, N-terminal domain [82173] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82174] (82 PDB entries)
   Uniprot P27487 39-776 ! Uniprot P27487 ! Uniprot P27487

8. Domain d3ccbb1: 3ccb B:36-508 [156246]
   Other proteins in same PDB: d3ccba2, d3ccbb2, d3ccbc2, d3ccbd2
   automated match to d1orva1
   complexed with b2y, nag

Details for d3ccbb1

PDB Entry: 3ccb, 2.49 Å

PDB Description: crystal structure of human dpp4 in complex with a benzimidazole derivative

PDB Compounds: (B:) dipeptidyl peptidase 4

SCOPe Domain Sequences for d3ccbb1:

Sequence, based on SEQRES records:

>d3ccbb1 b.70.3.1 (B:36-508) Dipeptidyl peptidase IV/CD26, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
hhhsrktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvflenstf
defghsindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwv
twspvghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalw
wspngtflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntds
lssvtnatsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessg
rwnclvarqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdct
fitkgtwevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercq
yysvsfskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvq

Sequence, based on observed residues (ATOM records):

>d3ccbb1 b.70.3.1 (B:36-508) Dipeptidyl peptidase IV/CD26, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
hhhsrktytltdylkntyrlklyslrwisdheylykqnilvfnaeygnssvflenstfde
fghsindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtw
spvghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwws
pngtflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdsls
svtnatsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrw
nclvarqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfi
tkgtwevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyy
svsfskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvq

Timeline for d3ccbb1:

• d3ccbb1 first appeared in SCOP 1.75
  
• d3ccbb1 appears in SCOPe 2.04
  
• d3ccbb1 appears in SCOPe 2.06
  
• d3ccbb1 appears in the current release, SCOPe 2.08