SCOPe 2.06: Domain d3c72b_: 3c72 B:

Lineage for d3c72b_ (3c72 B:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.102: alpha/alpha toroid [48207] (6 superfamilies)
   multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies

4. Superfamily a.102.4: Terpenoid cyclases/Protein prenyltransferases [48239] (5 families)

5. Family a.102.4.3: Protein prenyltransferases [48246] (3 proteins)

6. Protein Rab geranylgeranyltransferase, beta subunit [48249] (1 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [48250] (21 PDB entries)

8. Domain d3c72b_: 3c72 B: [155997]
   automated match to d1dceb_
   complexed with ca, cx1, zn

Details for d3c72b_

PDB Entry: 3c72, 2.3 Å

PDB Description: engineered rabggtase in complex with a peptidomimetic inhibitor

PDB Compounds: (B:) Geranylgeranyl transferase type-2 subunit beta

SCOPe Domain Sequences for d3c72b_:

Sequence, based on SEQRES records:

>d3c72b_ a.102.4.3 (B:) Rab geranylgeranyltransferase, beta subunit {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dvtiksdapdtlllekhadyiasygskkddyeycmseylrmsgvywgltvmdlmgqlhrm
nkeeilvfikscqhecggvsasighdphllytlsavqiltlydsihvinvdkvvayvqsl
qkedgsfagdiwgeidtrfsfcavatlallgkldainvekaiefvlscmnfdggfgcrpg
seshagqiycctgflaitsqlhqvnsdllgwwlcerqlpsgglngrpeklpdvcyswwvl
aslkiigrlhwidreklrsfilacqdeetggfadrpgdmvdpfhtlfgiaglsllgeeqi
kpvspvfcmpeevlqrvnvqpelvs

Sequence, based on observed residues (ATOM records):

>d3c72b_ a.102.4.3 (B:) Rab geranylgeranyltransferase, beta subunit {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dvtiksdapdtlllekhadyiasygskddyeycmseylrmsgvywgltvmdlmgqlhrmn
keeilvfikscqhecggvsasighdphllytlsavqiltlydsihvinvdkvvayvqslq
kedgsfagdiwgeidtrfsfcavatlallgkldainvekaiefvlscmnfdggfgcrpgs
eshagqiycctgflaitsqlhqvnsdllgwwlcerqlpsgglngrpeklpdvcyswwvla
slkiigrlhwidreklrsfilacqdeetggfadrpgdmvdpfhtlfgiaglsllgeeqik
pvspvfcmpeevlqrvnvqpelvs

Timeline for d3c72b_:

• d3c72b_ first appeared in SCOP 1.75, called d3c72b1
  
• d3c72b_ appears in SCOPe 2.05
  
• d3c72b_ appears in SCOPe 2.07
  
• d3c72b_ appears in the current release, SCOPe 2.08