SCOPe 2.05: Domain d3c5ga3: 3c5g A:386-575

Lineage for d3c5ga3 (3c5g A:386-575)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.218: Nucleotidyltransferase [81302] (1 superfamily)
   core: alpha-beta-turn-beta-X-beta-(alpha); mixed beta-sheet, order of core strands: 123

4. Superfamily d.218.1: Nucleotidyltransferase [81301] (16 families)

5. Family d.218.1.2: DNA polymerase beta-like [81300] (5 proteins)
   insert X in the core is an alpha-beta(2) unit; mixed 5-stranded sheet, order: 12543; contains extra C-terminal alpha+beta subdomain

6. Protein DNA polymerase lambda [102943] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102944] (26 PDB entries)

8. Domain d3c5ga3: 3c5g A:386-575 [155945]
   Other proteins in same PDB: d3c5ga1, d3c5ga2, d3c5gb1, d3c5gb2
   automated match to d1rzta3
   protein/DNA complex; complexed with d3t, edo, mg, na; mutant

Details for d3c5ga3

PDB Entry: 3c5g, 2.2 Å

PDB Description: structure of a ternary complex of the r517k pol lambda mutant

PDB Compounds: (A:) DNA polymerase lambda

SCOPe Domain Sequences for d3c5ga3:

Sequence, based on SEQRES records:

>d3c5ga3 d.218.1.2 (A:386-575) DNA polymerase lambda {Human (Homo sapiens) [TaxId: 9606]}
rmpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdvdvlithpdgrshrgifs
rlldslrqegfltddlvsqeengqqqkylgvcrlpgpgrrhrrldiivvpysefacally
ftgsahfnrsmkalaktkgmslsehalstavvrnthgckvgpgrvlptptekdvfrllgl
pyrepaerdw

Sequence, based on observed residues (ATOM records):

>d3c5ga3 d.218.1.2 (A:386-575) DNA polymerase lambda {Human (Homo sapiens) [TaxId: 9606]}
rmpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdvdvlithpdgrshrgifs
rlldslrqegfltddlvsqeengqqqkylgvcrlpgpgrrhrrldiivvpysefacally
ftgsahfnrsmkalaktkgmslsehalstavvhgckvgpgrvlptptekdvfrllglpyr
epaerdw

Timeline for d3c5ga3:

• d3c5ga3 first appeared in SCOP 1.75
  
• d3c5ga3 appears in SCOPe 2.04
  
• d3c5ga3 appears in SCOPe 2.06
  
• d3c5ga3 appears in the current release, SCOPe 2.08