SCOPe 2.05: Domain d3c0yc_: 3c0y C:

Lineage for d3c0yc_ (3c0y C:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
   automatically mapped to Pfam PF00850

6. Protein Histone deacetylase 7, HDAC7 [159582] (1 species)
   HDAC7a

7. Species Human (Homo sapiens) [TaxId:9606] [159583] (5 PDB entries)
   Uniprot Q8WUI4 515-900

8. Domain d3c0yc_: 3c0y C: [155843]
   automated match to d3c0ya1
   complexed with k, zn

Details for d3c0yc_

PDB Entry: 3c0y, 2.1 Å

PDB Description: Crystal structure of catalytic domain of human histone deacetylase HDAC7

PDB Compounds: (C:) Histone deacetylase 7a

SCOPe Domain Sequences for d3c0yc_:

Sequence, based on SEQRES records:

>d3c0yc_ c.42.1.2 (C:) Histone deacetylase 7, HDAC7 {Human (Homo sapiens) [TaxId: 9606]}
ttgliydsvmlkhqcscgdnsrhpehagriqsiwsrlqerglrsqceclrgrkasleelq
svhserhvllygtnplsrlkldngklagllaqrmfvmlpcggvgvdtdtiwnelhssnaa
rwaagsvtdlafkvasrelkngfavvrppghhadhstamgfcffnsvaiacrqlqqqska
skilivdwdvhhgngtqqtfyqdpsvlyislhrhddgnffpgsgavdevgagsgegfnvn
vawaggldppmgdpeylaafrivvmpiarefspdlvlvsagfdaaeghpaplggyhvsak
cfgymtqqlmnlaggavvlalegghdltaicdaseacvaallgnrvdplseegwkqkpnl
nairsleavirvhskywgcmq

Sequence, based on observed residues (ATOM records):

>d3c0yc_ c.42.1.2 (C:) Histone deacetylase 7, HDAC7 {Human (Homo sapiens) [TaxId: 9606]}
ttgliydsvmlkhqcscgdnsrhpehagriqsiwsrlqerglrsqceclrgrkasleelq
svhserhvllygtnlpcggvgvdtdtiwnelhssnaarwaagsvtdlafkvasrelkngf
avvrppghhadhstamgfcffnsvaiacrqlqqqskaskilivdwdvhhgngtqqtfyqd
psvlyislhrhddgnffpgsgavdevgagsgegfnvnvawaggldppmgdpeylaafriv
vmpiarefspdlvlvsagfdaaeghpaplggyhvsakcfgymtqqlmnlaggavvlaleg
ghdltaicdaseacvaallgnrvdplseegwkqkpnlnairsleavirvhskywgcmq

Timeline for d3c0yc_:

• d3c0yc_ first appeared in SCOP 1.75, called d3c0yc1
  
• d3c0yc_ appears in SCOPe 2.04
  
• d3c0yc_ appears in SCOPe 2.06
  
• d3c0yc_ appears in the current release, SCOPe 2.08