SCOPe 2.08: Domain d3blha1: 3blh A:8-325

Lineage for d3blha1 (3blh A:8-325)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cell division protein kinase 9, CDK9 [160810] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [160811] (6 PDB entries)
   Uniprot P50750 8-325

8. Domain d3blha1: 3blh A:8-325 [155393]
   Other proteins in same PDB: d3blhb1, d3blhb2
   complexed with trs

Details for d3blha1

PDB Entry: 3blh, 2.48 Å

PDB Description: crystal structure of human cdk9/cyclint1

PDB Compounds: (A:) Cell division protein kinase 9

SCOPe Domain Sequences for d3blha1:

Sequence, based on SEQRES records:

>d3blha1 d.144.1.7 (A:8-325) Cell division protein kinase 9, CDK9 {Human (Homo sapiens) [TaxId: 9606]}
vecpfcdevskyeklakigqgtfgevfkarhrktgqkvalkkvlmenekegfpitalrei
kilqllkhenvvnlieicrtkaspynrckgsiylvfdfcehdlagllsnvlvkftlseik
rvmqmllnglyyihrnkilhrdmkaanvlitrdgvlkladfglarafslaknsqpnrytn
rvvtlwyrppelllgerdygppidlwgagcimaemwtrspimqgnteqhqlalisqlcgs
itpevwpnvdnyelyeklelvkgqkrkvkdrlkayvrdpyaldlidkllvldpaqridsd
dalnhdffwsdpmpsdlk

Sequence, based on observed residues (ATOM records):

>d3blha1 d.144.1.7 (A:8-325) Cell division protein kinase 9, CDK9 {Human (Homo sapiens) [TaxId: 9606]}
vecpfcdevskyeklakigqgtfgevfkarhrktgqkvalkkvekegfpitalreikilq
llkhenvvnlieicrtsiylvfdfcehdlagllsnvlvkftlseikrvmqmllnglyyih
rnkilhrdmkaanvlitrdgvlkladfglarafslpnrytnrvvtlwyrppelllgerdy
gppidlwgagcimaemwtrspimqgnteqhqlalisqlcgsitpevwpnvdnylvkgqkr
kvkdrlkayvrdpyaldlidkllvldpaqridsddalnhdffwsdpmpsdlk

Timeline for d3blha1:

• d3blha1 first appeared in SCOP 1.75
  
• d3blha1 appears in SCOPe 2.07