Lineage for d3bi1a3 (3bi1 A:57-117,A:351-593)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2125386Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 2126724Superfamily c.56.5: Zn-dependent exopeptidases [53187] (10 families) (S)
    core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest
  5. 2127054Family c.56.5.5: FolH catalytic domain-like [53210] (2 protein domains)
  6. 2127055Protein Glutamate carboxypeptidase II FOLH1 [142522] (1 species)
    Folate hydrolase 1, FolH homologue
  7. 2127056Species Human (Homo sapiens) [TaxId:9606] [142523] (24 PDB entries)
    Uniprot Q04609 57-117,351-593
  8. 2127057Domain d3bi1a3: 3bi1 A:57-117,A:351-593 [155297]
    Other proteins in same PDB: d3bi1a1, d3bi1a2
    automatically matched to d1z8la3
    complexed with 3bi, ca, cl, nag, zn

Details for d3bi1a3

PDB Entry: 3bi1 (more details), 1.5 Å

PDB Description: X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a transition state analog of methotrexate-Glu
PDB Compounds: (A:) glutamate carboxypeptidase 2

SCOPe Domain Sequences for d3bi1a3:

Sequence; same for both SEQRES and ATOM records: (download)

>d3bi1a3 c.56.5.5 (A:57-117,A:351-593) Glutamate carboxypeptidase II FOLH1 {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3bi1a3:

Click to download the PDB-style file with coordinates for d3bi1a3.
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Timeline for d3bi1a3: