Lineage for d3bgqa_ (3bgq A:)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2586062Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2586063Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2586210Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2589317Protein Proto-oncogene serine/threonine-protein kinase Pim-1 [118133] (1 species)
    OPK group(?); PIM subfamily; serine/threonine kinase
  7. 2589318Species Human (Homo sapiens) [TaxId:9606] [118134] (110 PDB entries)
    Uniprot P11309 33-305 ! Uniprot P11309 32-308
  8. 2589336Domain d3bgqa_: 3bgq A: [155251]
    automated match to d4k18a_
    complexed with vx2

Details for d3bgqa_

PDB Entry: 3bgq (more details), 2 Å

PDB Description: Human Pim-1 kinase in complex with an triazolo pyridazine inhibitor VX2
PDB Compounds: (A:) Proto-oncogene serine/threonine-protein kinase Pim-1

SCOPe Domain Sequences for d3bgqa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3bgqa_ d.144.1.7 (A:) Proto-oncogene serine/threonine-protein kinase Pim-1 {Human (Homo sapiens) [TaxId: 9606]}
plesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvl
lkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvl
eavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppew
iryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecqhlirwcla
lrpsdrptfeeiqnhpwmqdvllpqetaeihlh

SCOPe Domain Coordinates for d3bgqa_:

Click to download the PDB-style file with coordinates for d3bgqa_.
(The format of our PDB-style files is described here.)

Timeline for d3bgqa_: