SCOPe 2.06: Domain d3b4vf_: 3b4v F:

Lineage for d3b4vf_ (3b4v F:)

1. Root: SCOPe 2.06

2. Class g: Small proteins [56992] (94 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 proteins)

6. Protein Activin A (Inhibin beta A) [90170] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [90171] (8 PDB entries)
   Uniprot P08476 311-426

8. Domain d3b4vf_: 3b4v F: [154828]
   automated match to d1s4yb_
   complexed with edo, nag, so4

Details for d3b4vf_

PDB Entry: 3b4v, 2.48 Å

PDB Description: x-ray structure of activin in complex with fstl3

PDB Compounds: (F:) Inhibin beta A chain

SCOPe Domain Sequences for d3b4vf_:

Sequence, based on SEQRES records:

>d3b4vf_ g.17.1.2 (F:) Activin A (Inhibin beta A) {Human (Homo sapiens) [TaxId: 9606]}
glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

Sequence, based on observed residues (ATOM records):

>d3b4vf_ g.17.1.2 (F:) Activin A (Inhibin beta A) {Human (Homo sapiens) [TaxId: 9606]}
glecgvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhstv
inhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

Timeline for d3b4vf_:

• d3b4vf_ first appeared in SCOP 1.75, called d3b4vf1
  
• d3b4vf_ appears in SCOPe 2.05
  
• d3b4vf_ appears in SCOPe 2.07
  
• d3b4vf_ appears in the current release, SCOPe 2.08