SCOP 1.75: Domain d3b4vb1: 3b4v B:1-116

Lineage for d3b4vb1 (3b4v B:1-116)

1. Root: SCOP 1.75

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (7 families)

5. Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (7 proteins)

6. Protein Activin A (Inhibin beta A) [90170] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [90171] (8 PDB entries)
   Uniprot P08476 311-426

8. Domain d3b4vb1: 3b4v B:1-116 [154826]
   automatically matched to d1s4yb_
   complexed with edo, nag, so4

Details for d3b4vb1

PDB Entry: 3b4v, 2.48 Å

PDB Description: x-ray structure of activin in complex with fstl3

PDB Compounds: (B:) Inhibin beta A chain

SCOP Domain Sequences for d3b4vb1:

Sequence, based on SEQRES records:

>d3b4vb1 g.17.1.2 (B:1-116) Activin A (Inhibin beta A) {Human (Homo sapiens) [TaxId: 9606]}
glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

Sequence, based on observed residues (ATOM records):

>d3b4vb1 g.17.1.2 (B:1-116) Activin A (Inhibin beta A) {Human (Homo sapiens) [TaxId: 9606]}
glecgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtgsslsfhstv
inhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

Timeline for d3b4vb1:

• d3b4vb1 is new in SCOP 1.75
  
• d3b4vb1 is called d3b4vb_ in SCOPe 2.01
  
• d3b4vb1 appears in the current release, SCOPe 2.08, called d3b4vb_