Lineage for d3b2wa_ (3b2w A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2219897Protein Lymphocyte kinase (lck) [56153] (1 species)
    PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase
  7. 2219898Species Human (Homo sapiens) [TaxId:9606] [56154] (34 PDB entries)
  8. 2219927Domain d3b2wa_: 3b2w A: [154804]
    automated match to d1qpca_
    complexed with 9nh

Details for d3b2wa_

PDB Entry: 3b2w (more details), 2.3 Å

PDB Description: Crystal structure of pyrimidine amide 11 bound to Lck
PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase LCK

SCOPe Domain Sequences for d3b2wa_:

Sequence, based on SEQRES records: (download)

>d3b2wa_ d.144.1.7 (A:) Lymphocyte kinase (lck) {Human (Homo sapiens) [TaxId: 9606]}
wevpretlklverlgagqfgevwmgyynghtkvavkslkqgsmspdaflaeanlmkqlqh
qrlvrlyavvtqepiyiiteymengslvdflktpsgikltinklldmaaqiaegmafiee
rnyihrdlraanilvsdtlsckiadfglarliedneytaregakfpikwtapeainygtf
tiksdvwsfgillteivthgripypgmtnpeviqnlergyrmvrpdncpeelyqlmrlcw
kerpedrptfdylrsvledffta

Sequence, based on observed residues (ATOM records): (download)

>d3b2wa_ d.144.1.7 (A:) Lymphocyte kinase (lck) {Human (Homo sapiens) [TaxId: 9606]}
wevpretlklverlgagqfgevwmgyynghtkvavkslkqgsmspdaflaeanlmkqlqh
qrlvrlyavvtqepiyiiteymengslvdflktpsgikltinklldmaaqiaegmafiee
rnyihrdlraanilvsdtlsckiadfglarliedneytagakfpikwtapeainygtfti
ksdvwsfgillteivthgripypgmtnpeviqnlergyrmvrpdncpeelyqlmrlcwke
rpedrptfdylrsvledffta

SCOPe Domain Coordinates for d3b2wa_:

Click to download the PDB-style file with coordinates for d3b2wa_.
(The format of our PDB-style files is described here.)

Timeline for d3b2wa_: