SCOPe 2.02: Domain d3b2ub2: 3b2u B:481-502

Lineage for d3b2ub2 (3b2u B:481-502)

1. Root: SCOPe 2.02

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.9: Growth factor receptor domain [57184] (1 family)

5. Family g.3.9.1: Growth factor receptor domain [57185] (9 proteins)

6. Protein EGF receptor Cys-rich domains [82887] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82888] (6 PDB entries)

8. Domain d3b2ub2: 3b2u B:481-502 [154773]
   Other proteins in same PDB: d3b2ua1, d3b2ub1, d3b2uc1, d3b2uc2, d3b2ue1, d3b2uf1, d3b2uf2, d3b2uh1, d3b2uh2, d3b2ui1, d3b2uj1, d3b2uj2, d3b2um1, d3b2un1, d3b2un2, d3b2up1, d3b2uq1, d3b2uq2, d3b2us1, d3b2ut1, d3b2ut2, d3b2uv1, d3b2uw1, d3b2uw2
   automatically matched to d1ivoa4
   complexed with nag, so4

Details for d3b2ub2

PDB Entry: 3b2u, 2.58 Å

PDB Description: crystal structure of isolated domain iii of the extracellular region of the epidermal growth factor receptor in complex with the fab fragment of imc-11f8

PDB Compounds: (B:) Epidermal growth factor receptor

SCOPe Domain Sequences for d3b2ub2:

Sequence; same for both SEQRES and ATOM records:

>d3b2ub2 g.3.9.1 (B:481-502) EGF receptor Cys-rich domains {Human (Homo sapiens) [TaxId: 9606]}
vchalcspegcwgpeprdcvsc

Timeline for d3b2ub2:

• d3b2ub2 first appeared in SCOP 1.75
  
• d3b2ub2 appears in SCOPe 2.01
  
• d3b2ub2 appears in SCOPe 2.03
  
• d3b2ub2 appears in the current release, SCOPe 2.08