SCOP 1.75: Domain d2zm3b1: 2zm3 B:982-1285

Lineage for d2zm3b1 (2zm3 B:982-1285)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Insulin-like growth factor 1 receptor [69825] (1 species)
   PTK group; InsR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [69826] (6 PDB entries)

8. Domain d2zm3b1: 2zm3 B:982-1285 [154685]
   automatically matched to d1m7na_
   complexed with 575

Details for d2zm3b1

PDB Entry: 2zm3, 2.5 Å

PDB Description: Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor

PDB Compounds: (B:) insulin-like growth factor 1 receptor

SCOP Domain Sequences for d2zm3b1:

Sequence, based on SEQRES records:

>d2zm3b1 d.144.1.7 (B:982-1285) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
saadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasm
rerieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemenn
pvlappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiy
etdyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqv
lrfvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyy
seen

Sequence, based on observed residues (ATOM records):

>d2zm3b1 d.144.1.7 (B:982-1285) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
saadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasm
rerieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpeapps
lskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrk
ggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmeg
glldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseen

Timeline for d2zm3b1:

• d2zm3b1 is new in SCOP 1.75
  
• d2zm3b1 is called d2zm3b_ in SCOPe 2.01
  
• d2zm3b1 appears in the current release, SCOPe 2.08, called d2zm3b2