Lineage for d2zm3a2 (2zm3 A:981-1285)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2544005Protein Insulin-like growth factor 1 receptor [69825] (1 species)
    PTK group; InsR subfamily; membrane spanning protein tyrosine kinase
  7. 2544006Species Human (Homo sapiens) [TaxId:9606] [69826] (18 PDB entries)
  8. 2544023Domain d2zm3a2: 2zm3 A:981-1285 [154684]
    Other proteins in same PDB: d2zm3a3, d2zm3b3, d2zm3c3, d2zm3d3
    automated match to d1p4ob_
    complexed with 575

Details for d2zm3a2

PDB Entry: 2zm3 (more details), 2.5 Å

PDB Description: Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor
PDB Compounds: (A:) insulin-like growth factor 1 receptor

SCOPe Domain Sequences for d2zm3a2:

Sequence, based on SEQRES records: (download)

>d2zm3a2 d.144.1.7 (A:981-1285) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
fsaadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaas
mrerieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemen
npvlappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdi
yetdyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneq
vlrfvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfy
yseen

Sequence, based on observed residues (ATOM records): (download)

>d2zm3a2 d.144.1.7 (A:981-1285) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
fsaadvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaas
mrerieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpenpv
lappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyet
dyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlr
fvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyse
en

SCOPe Domain Coordinates for d2zm3a2:

Click to download the PDB-style file with coordinates for d2zm3a2.
(The format of our PDB-style files is described here.)

Timeline for d2zm3a2: