SCOPe 2.08: Domain d2zkmx4: 2zkm X:312-660

Lineage for d2zkmx4 (2zkm X:312-660)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.18: PLC-like phosphodiesterases [51695] (4 families)

5. Family c.1.18.1: Mammalian PLC [51696] (2 proteins)

6. Protein Phospholipase C-beta-2 [159421] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [159422] (2 PDB entries)
   Uniprot Q00722 312-660

8. Domain d2zkmx4: 2zkm X:312-660 [154590]
   Other proteins in same PDB: d2zkmx1, d2zkmx2, d2zkmx3
   automatically matched to 2FJU B:312-660
   complexed with ca

Details for d2zkmx4

PDB Entry: 2zkm, 1.62 Å

PDB Description: crystal structure of phospholipase c beta 2

PDB Compounds: (X:) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2

SCOPe Domain Sequences for d2zkmx4:

Sequence, based on SEQRES records:

>d2zkmx4 c.1.18.1 (X:312-660) Phospholipase C-beta-2 {Human (Homo sapiens) [TaxId: 9606]}
hdmtqplnhyfinsshntyltagqfsglssaemyrqvllsgcrcveldcwkgkppdeepi
ithgftmttdiffkeaieaiaesafktspypiilsfenhvdsprqqakmaeycrtifgdm
llteplekfplkpgvplpspedlrgkiliknkknqfsgptssskdtggeaegssppsapa
vwageegteleeeeveeeeeeesgnldeeeikkmqsdegtaglevtayeemsslvnyiqp
tkfvsfefsaqknrsyvissftelkaydllskasvqfvdynkrqmsriypkgtrmdssny
mpqmfwnagcqmvalnfqtmdlpmqqnmavfefngqsgyllkhefmrrp

Sequence, based on observed residues (ATOM records):

>d2zkmx4 c.1.18.1 (X:312-660) Phospholipase C-beta-2 {Human (Homo sapiens) [TaxId: 9606]}
hdmtqplnhyfinsshntyltagqfsglssaemyrqvllsgcrcveldcwkgkppdeepi
ithgftmttdiffkeaieaiaesafktspypiilsfenhvdsprqqakmaeycrtifgdm
llteplekfplkpgvplpspedlrgkiliknkknnldeeeikkmqsdegtaglevtayee
msslvnyiqptkfvsfefsaqknrsyvissftelkaydllskasvqfvdynkrqmsriyp
kgtrmdssnympqmfwnagcqmvalnfqtmdlpmqqnmavfefngqsgyllkhefmrrp

Timeline for d2zkmx4:

• d2zkmx4 first appeared in SCOP 1.75
  
• d2zkmx4 appears in SCOPe 2.07