SCOP 1.75: Domain d2zkmx1: 2zkm X:142-311

Lineage for d2zkmx1 (2zkm X:142-311)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.39.1: EF-hand [47473] (11 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

5. Family a.39.1.7: EF-hand modules in multidomain proteins [47547] (8 proteins)

6. Protein Phospholipase C-beta-2 [158478] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [158479] (2 PDB entries)
   Uniprot Q00722 142-311

8. Domain d2zkmx1: 2zkm X:142-311 [154587]
   Other proteins in same PDB: d2zkmx2, d2zkmx3, d2zkmx4
   automatically matched to 2FJU B:142-311
   complexed with ca

Details for d2zkmx1

PDB Entry: 2zkm, 1.62 Å

PDB Description: crystal structure of phospholipase c beta 2

PDB Compounds: (X:) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2

SCOP Domain Sequences for d2zkmx1:

Sequence, based on SEQRES records:

>d2zkmx1 a.39.1.7 (X:142-311) Phospholipase C-beta-2 {Human (Homo sapiens) [TaxId: 9606]}
asrstfldkilvklkmqlnsegkipvknffqmfpadrkrveaalsachlpkgkndainpe
dfpepvyksflmslcprpeideiftsyhakakpymtkehltkfinqkqrdsrlnsllfpp
arpdqvqglidkyepsginaqrgqlspegmvwflcgpensvlaqdklllh

Sequence, based on observed residues (ATOM records):

>d2zkmx1 a.39.1.7 (X:142-311) Phospholipase C-beta-2 {Human (Homo sapiens) [TaxId: 9606]}
asrstfldkilvklkmqlnsegkipvknffqmfpadrkrveaalsachlpkgkndainpe
dfpepvyksflmslcprpeideiftymtkehltkfinqkqrqvqglidkyepslspegmv
wflcgpensvlaqdklllh

Timeline for d2zkmx1:

• d2zkmx1 is new in SCOP 1.75
  
• d2zkmx1 appears in SCOPe 2.01
  
• d2zkmx1 appears in the current release, SCOPe 2.08