Lineage for d2zdua1 (2zdu A:46-400)

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 874255Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 874256Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 874317Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 874380Protein c-jun N-terminal kinase (jnk3s) [56137] (1 species)
    CMGC group; ERK/MAPK subfamily; serine/threonine kinase
  7. 874381Species Human (Homo sapiens) [TaxId:9606] [56138] (16 PDB entries)
  8. 874395Domain d2zdua1: 2zdu A:46-400 [154401]
    automatically matched to d1jnka_
    complexed with 446

Details for d2zdua1

PDB Entry: 2zdu (more details), 2.5 Å

PDB Description: Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor
PDB Compounds: (A:) Mitogen-activated protein kinase 10

SCOP Domain Sequences for d2zdua1:

Sequence, based on SEQRES records: (download)

>d2zdua1 d.144.1.7 (A:46-400) c-jun N-terminal kinase (jnk3s) {Human (Homo sapiens) [TaxId: 9606]}
nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfmmtpyvv
tryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpe
fmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpa
krisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliykevmn

Sequence, based on observed residues (ATOM records): (download)

>d2zdua1 d.144.1.7 (A:46-400) c-jun N-terminal kinase (jnk3s) {Human (Homo sapiens) [TaxId: 9606]}
nqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqtha
krayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglavtryyrapevilgm
gykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrnyv
enrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhpy
invwydpaevearehtieewkeliykevmn

SCOP Domain Coordinates for d2zdua1:

Click to download the PDB-style file with coordinates for d2zdua1.
(The format of our PDB-style files is described here.)

Timeline for d2zdua1: